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The toxicological data reporting indicates that any type of study may be submitted, implying the possibility to submit NAMs for informing potential hazard concerns for genotoxicity, carcinogenicity, respiratory toxicity, reproductive toxicity, cardiopulmonary toxicity, and any other type of toxicity

Castoreum has a deep, sensuous, tenacious, leathery, woody scent, often with smoky undertones and hints of forest trees and plants

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Furthermore, allergen exposured skin elicits the level of eosinophil of allergen unexposed mucosal organs and causes allergic inflammation, including the lungs and gut (Olbrich et al., 2020)